How and why spermatozoa cause calcium oscillations in mammalian oocytes.
نویسندگان
چکیده
Relationship between latency and period for 5-hydroxytryptamine-induced membrane responses in the Calliphora salivary gland. (1993) Fertilization and thimerosal stimulate similar calcium spiking patterns in mouse oocytes but by separate mechanisms. (19%) Phospholipase C in mouse oocytes: characterisation of ,p" and y isoforms and their possible involvement in sperm-induced Ca 2+ spiking. (1994) Regenerative and non-regenerative calcium transients in hamster eggs triggered by inositol 1,4,5-trisphosphate. The ryanodine receptor/ calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues. Effects of altered extracellular and intracellular calcium-concentration on hyperpolarizing responses of the hamster egg. ryanodine, and sperm induced Ca 2+ release increase dunng meiotic maturation of mouse oocytes. Regulation of intracellular calcium in the mouse egg: evidence for inositol trisphosphate-induced calcium release, but not calcium-induced calcium release. (1996) A direct measurement of increased divalent cation influx in fertilized mouse oocytes.
منابع مشابه
Effects of protein kinase C activation and inhibition on sperm-, thimerosal-, and ryanodine-induced calcium responses of human oocytes.
Previous data have shown that protein kinase C (PKC) participates in the mechanism of sperm-induced calcium oscillations in mammalian oocytes, but the actual role of this enzyme in the oscillation mechanism is still unknown. In this study we show that drugs modulating PKC activity disturb the oscillations induced by spermatozoa, thimerosal and ryanodine, but in a different way for each of the t...
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In oocytes from all mammalian species studied to date, fertilization by a spermatozoon induces intracellular calcium ([Ca(2+)](i)) oscillations that are crucial for appropriate oocyte activation and embryonic development. Such patterns are species-specific and have not yet been elucidated in horses; it is also not known whether equine oocytes respond with transient [Ca(2+)](i) oscillations when...
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The two questions posed by Tesarik (1998) and Swann et al. (1998) on the nature of sperm factor are: (i) if glucosamine6-phosphate deaminase is not the ‘so-called oscillogen’, as shown by the recombinant studies of Wolosker et al. (1998), what is the nature of sperm factor?; and (ii) is there a dual mechanism for oocyte activation involving signals from soluble sperm factors together with signa...
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عنوان ژورنال:
- Molecular human reproduction
دوره 2 6 شماره
صفحات -
تاریخ انتشار 1996